Vacation Rentals Fort Myers - Vacation Rentals in Mesilla

Casita Azul, Mesilla Plaza Only Steps Away From US $198
         

10.0 (195 Reviews)
House
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  • Pet Friendly
Rustic Las Cruces Escape - 2 Mi to NMSU! From US $236
         

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10.0 (10 Reviews)
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Ramada Hotel & Conference Center by Wyndham Las Cruces From US $92
         

Private Oasis Near Old Mesilla - Home with an In-Ground Pool! From US $263
         

"Casa de Maíz" centrally located - close to NMSU From US $163
         

10.0 (51 Reviews)
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  • Pet Friendly
Adorable 2 BR at the heart of town! From US $120
         

10.0 (50 Reviews)
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  • Pool
Rustic Las Cruces Escape - 2 Mi to NMSU! From US $182
         

10.0 (41 Reviews)
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  • TV

Luxury Places to Stay in Mesilla

Over 177+ Luxury Places to Stay in or Near Mesilla
Southwestern Hilltop Retreat + Pool From US $586
         

10.0 (8 Reviews)
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  • Pet Friendly
Motel 9 Las Cruces From US $454
         

5.6 (74 Reviews)
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Las Cruces Santa Fe-Style Adobe Home on 6 Acres! From US $453
         

Las Cruces Santa Fe-Style Adobe Home on 6 Acres! From US $343
         

Ponderosa de Mesilla From US $307
         

10.0 (9 Reviews)
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Las Cruces Home w/Fenced Yard: Recently Remodeled From US $263
         

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6.5 (2 Reviews)
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Top-Rated Vacation Rentals with a Pool in Mesilla

Over 47+ Top-Rated Vacation Rentals with a Pool in or Near Mesilla
MESILLA OUTPOST From US $197
         

10.0 (27 Reviews)
Condo
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*Casa Bonita de Mesilla* From US $153
         

9.8 (34 Reviews)
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Condo 124E in Historic Mesilla From US $146
         

9.8 (31 Reviews)
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Sancho's Condo De Mesilla From US $105
         

9.8 (14 Reviews)
Condo
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  • Pet Friendly
Drury Inn & Suites Las Cruces From US $137
         

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9.2 (733 Reviews)
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Pet-Friendly Vacation Rentals in Mesilla

Over 70+ Pet-Friendly Vacation Rentals in or Near Mesilla
Southwestern Comfort Stay 2B From US $143
         

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9.6 (12 Reviews)
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Encanto de Mesilla - Comfort and Taste! From US $145
         

10.0 (49 Reviews)
Condo
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2 bed, yard, pet friendly in Historic Mesilla. From US $173
         

10.0 (2 Reviews)
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  • Pet Friendly
3 bed 2 bath Hacienda near Downtown and NMSU. From US $234
         

10.0 (1 Review)
House
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Historic Mesilla Adobe Home near the Plaza From US $103
         

9.6 (43 Reviews)
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Cozy 1-bedroom bungalow in amazing Las Cruces with AC From US $111
         

8.8 (3 Reviews)
House
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  • Pet Friendly
See More Pet-Friendly Vacation Rentals in Mesilla on PetFriendly.io

Large Vacation Homes & Villas in Mesilla

Over 5+ Large Vacation Homes & Villas in or Near Mesilla
Econo Lodge Las Cruces University Area From US $64
         

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5.3 (42 Reviews)
Cabin
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1 Mi to NMSU! Las Cruces Home w/Pet-Friendly Yard From US $194
         

9.4 (3 Reviews)
House
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  • Parking
  • Pet Friendly

Wheelchair Accessible Vacation Homes in Mesilla

Over 17+ Wheelchair Accessible Vacation Homes in or Near Mesilla
Stay, Relax, and Enjoy From US $99
         

8.0 (3 Reviews)
House
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  • Pet Friendly
  • Pool
Courtyard by Marriott Las Cruces at NMSU From US $149
         

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9.1 (100 Reviews)
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Drury Inn & Suites Las Cruces From US $123
         

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9.4 (1009 Reviews)
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Hampton Inn & Suites Las Cruces I-10, Nm From US $132
         

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8.6 (189 Reviews)
Hotel
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Courtyard by Marriott Las Cruces at NMSU From US $165
         

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9.2 (557 Reviews)
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Comfort Inn & Suites Las Cruces Mesilla From US $119
         

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8.3 (334 Reviews)
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  • Pet Friendly
Hampton Inn & Suites Las Cruces I-10 From US $121
         

8.8 (1000 Reviews)
Hotel
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Best Western Mission Inn From US $93
         

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8.2 (864 Reviews)
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Mesilla Vacation Rentals and Airbnb Places to Stay Under $200

Over 114+ Mesilla Vacation Rentals and Airbnb Places to Stay Under $200
Las Cruces Studio ~ 3 Mi to NMSU! From US $156
         

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9.3 (4 Reviews)
Apartment
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Best Western Mission Inn From US $99
         

8.8 (1224 Reviews)
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2 bed and pullout sofa kids and dogs welcome From US $128
         

Casa Del Sol - Peaceful Retreat In Beautiful Mesilla. From US $100
         

Charming Adobe Casita in Old Mesilla - near NMSU From US $126
         

Charming 2-bedroom Casita In Mesilla Park From US $105
         

Instantly Bookable Vacation Homes in Mesilla

Over 51+ Instantly Bookable Vacation Homes in or Near Mesilla
Vintage 80's Retro RV Experience, Back to 1985! From US $70
         

Spacious 4BR Retreat Near Historic Old Mesilla From US $214
         

2 bed with W/D, pets ok, 5 min to Farmers Market From US $138
         

8.0 (1 Review)
House
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  • Pet Friendly
Downtown Las Cruses Apartment with Fine Art Collection From US $79
         

8.0 (1 Review)
Apartment
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  • Parking
  • Pet Friendly

About Mesilla Vacation Rentals

With more than 186 Mesilla vacation rentals, we can help you find a place to stay. These rentals, including vacation rentals, Vacationrentalsfortmyers and other short-term private accommodations, have top-notch amenities with the best value, providing you with comfort and luxury at the same time. Get more value and more room when you stay at a rental property in Mesilla.

Looking for last-minute deals, or finding the best deals available for cottages, condos, private villas, and large vacation homes? With Vacationrentalsfortmyers Mesilla, you have the flexibility of comparing different options of various deals with a single click. Looking for a rental by owner with the best swimming pools, hot tubs, allows pets, or even those with huge master suite bedrooms and have large screen televisions? You can find vacation rentals by owner, and other popular Airbnb-style properties in Mesilla. Places to stay near Mesilla are 981.03 ft² on average, with prices averaging US $159 a night.

Vacationrentalsfortmyers makes it easy and safe to find and compare vacation rentals in Mesilla with prices often at a 30-40% discount versus the price of a hotel. Just search for your destination and secure your reservation today.

Top Rental Accommodation Types in Mesilla

Type Count
Vacation Homes 94
Hotels 30
Holiday Apartments 27
Cottages 3
B&B 1
Cabin Rentals 1
Others 1
Ski Chalet Rentals 1

Use these Quick Filters to Find a Vacation Rental in Mesilla

Pro Tip: Vacationrentalsfortmyers makes it easy to compare the best listings on Vacationrentalsfortmyers homes from online vacation rental OTAs, including Booking.com and more. Use the Advanced Filter feature at the top to easily flip between Vacationrentalsfortmyers homes, vacation rentals, bed and breakfasts, private Airbnb-style rentals availability, eco-friendly properties, property type, cancellation policies, prices, and several different options. All these make it easier to find the perfect accommodation for your next vacation in Mesilla.

Weather in Mesilla

View the weather forecast for Mesilla before booking your Mesilla Vacation Rentals to confirm your best time to go.

December - February
High 60°F       Low 26°F
March - May
High 77°F       Low 40°F
June - August
High 91°F       Low 64°F
September - November
High 84°F       Low 38°F

Mesilla Vacation Rental Frequently Asked Questions

What are the top vacation rentals in Mesilla?
How many vacation rentals are available in Mesilla?

Currently, the total number of properties listed in 2026 is over 186 in the Mesilla area, and still counting. By aggregating listings from multiple websites, offers an immense amount of choice of the best properties in Mesilla.